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Related Video New face of U.S. woman mauled by chimp Thu, Aug 11 2011 A combination photo shows face transplant recipient Charla Nash, of Stamford, Connecticut, before her injury and after her surgery. Credit: Reuters/Brigham and Women’s Hospital By Lauren Keiper BOSTON | Thu Aug 11, 2011 2:22pm EDT BOSTON (Reuters) – A woman who underwent a full face transplant in May after being mauled by a chimpanzee in 2009 revealed her new face in a photo released on Thursday. Charla Nash, 57, who was photographed in her hospital bed at Brigham and Women’s Hospital in Boston, appears dramatically different with a new nose, lips and facial skin. “I will now be able to do things I once took for granted,” Nash said in a statement. “I will be able to smell. I will be able to eat normally. I will no longer be disfigured. I will have lips and will speak clearly once again. I will be able to kiss and hug loved ones.” Nash was hurt after a friend’s 200-pound (91 kg) pet chimpanzee went on a rampage two years ago. She lost her hands, lips, nose and eyes, leaving her blind and disfigured after the attack. The animal was eventually shot and killed by police. After undergoing a grueling 20-hour full face transplant at the hospital in May, Nash in the photo now has a fair, almost blushing, complexion. Prior to the surgery, Nash was often photographed wearing a veil to hide her disfigurement. Nash’s full face transplant was the third surgery of its kind performed in the United States, all at the same hospital. An anonymous female donor provided face, hands and other tissue material that made the surgery possible. The hand transplant was deemed successful but the hands did not thrive after complications from pneumonia and were removed. Another hand transplant could be attempted if a suitable donor is identified, doctors have said. Nash’s face was rebuilt by a medical team of more than 30 physicians, nurses, anesthesiologists and residents in a challenging surgery made more complex by the double hand transplant. The world’s first full face transplant was completed in Spain in 2010. (Editing by Barbara Goldberg, Peter Bohan and Eric Beech )

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A smoker lights a cigarette in downtown Toronto February 19, 2007. Credit: Reuters/J.P. Moczulski By Eric Schultz NEW YORK | Fri Jul 22, 2011 10:15am EDT NEW YORK (Reuters Health) – After a heart attack, quitting smoking may offer a patient more benefits than any medication, but Italian researchers say the flipside is that resuming smoking after leaving the hospital can raise the same patient’s risk of dying as much as five-fold. On average, people who started smoking again after being hospitalized for acute coronary syndrome (ACS) — crushing chest pain that often signals a heart attack — were more than three times as likely to die within a year as people who successfully quit in a study led by Dr. Furio Colivicchi of San Filippo Neri Hospital in Rome. “Relapse is a major risk factor for long term survival,” said Dr. David Katz, associate professor of internal medicine at University of Iowa Carver College of Medicine in Iowa City. Quitting smoking has a similar lifesaving effect for ACS patients as taking recommended drugs to lower blood pressure or cholesterol, added Katz, who was not involved in the new study. To gauge the effects of resuming smoking after a heart “event,” and to see how many people are likely to relapse, Colivicchi and his colleagues tracked 1294 patients who reported being regular smokers before they were hospitalized with ACS. All the participants had ceased smoking while in the hospital and declared themselves motivated to continue abstaining once they were released. Patients received a few brief smoking-cessation counseling sessions while in the hospital, but no further counseling, nicotine replacement or other smoking-cessation help was provided after they left the hospital. The researchers interviewed patients about their smoking status at one, six, and 12 months after their release from the hospital and found that a total of 813 (63 percent) had relapsed by the end of the first year. About half had begun smoking again within 20 days of leaving the hospital. Within a year, 97 patients died, with 81 of those deaths attributed to cardiovascular causes, according to findings published in the American Journal of Cardiology. After adjusting for patient ages and other variables, the researchers found that resuming smoking raised a person’s risk of death three-fold compared to patients who didn’t relapse. The earlier a patient fell off the wagon, the more likely he or she was to die within a year — those who resumed smoking within 10 days of leaving the hospital were five times as likely to die as those who continued to abstain. Very few patients relapsed after being smoke-free for six months. “If you manage to stay off cigarettes for six months, you probably have the addiction beat,” said Dr. Nancy Rigotti, director of the Tobacco Research and Treatment Unit at Massachusetts General Hospital in Boston, who was not involved in the study. Colivicchi’s group did not measure how often the patients smoked — an important predictor of relapse and early death, Katz noted. Nonetheless, the results indicate a need to improve the way doctors help patients quit smoking, said Rigotti. “People don’t take treating tobacco use seriously in the medical setting,” and recommended treatments have not made their way into practice, she said. Colivicchi agreed. A successful program to help patients quit should take “a comprehensive long-term approach, including individual counseling, post-discharge support and pharmacological treatment,” he told Reuters Health in an email. A recent study from Harvard Medical School suggested that a comprehensive anti-smoking counseling program for heart attack patients could save thousands of lives at a relatively low cost. These findings, along with the results of the Italian study, said Rigotti, suggest that hospitals and insurers should work together to implement comprehensive anti-smoking programs to continue to help patients after they leave the hospital. SOURCE: bit.ly/nbuaPz American Journal of Cardiology, online July 7, 2011.

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